Developmental regulation of lck gene expression in T lymphocytes.
نویسندگان
چکیده
منابع مشابه
Developmental regulation of lck gene expression in T lymphocytes
In the mouse and human, mRNA transcripts encoding the lymphocyte-specific protein tyrosine kinase p56lck are derived from two separate promoters resulting in heterogeneity in the 5' untranslated region sequence. The proximal promoter lies just 5' to the coding region for the gene and is active only in thymocytes. In contrast, the distal promoter lies 34 kilobases (kb) 5' in the human, and is ac...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1991
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.173.2.383